How Poor Metabolic Health Allows Covid-19 to Hijack Our System with Dr. Ronesh Sinha



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When we think about Covid-19 and our health and well-being, there are many factors to consider. It’s not just about the general idea of immunity; we need to understand that multiple processes within the body can either make us more resilient against or more susceptible to this specific virus. Metabolic health is a big part of this. 

When we look at who is most vulnerable to Covid-19, we see that among the immuno-compromised and elderly there is also a population with major metabolic risk factors. That means insulin resistance, high triglycerides, low HDL cholesterol, obesity, hypertension, and more. 

Today on The Dhru Purohit Podcast, Dhru talks to Dr. Ronesh Sinha about the key areas we can focus on to optimize our metabolic health and how they specifically relate to decreasing our risk of severe outcomes from Covid-19.

Dr. Sinha, author of The South Asian Health Solution, is an internal medicine physician who runs a lifestyle clinic in Silicon Valley focused on reversing insulin resistance in ethnically diverse patients. He is also an expert in corporate wellness and serves as the Chief Medical Officer for Silicon Valley Employer Forum where he serves as a global adviser to shape health benefits for over 55 major Silicon Valley companies.

 His groundbreaking work in corporate wellness and raising awareness about insulin resistance in the Asian population has received global attention with front cover stories in Fortune Magazine and the LA Times. Dr. Sinha blogs actively on health at and recently launched the Meta Health podcast where he uses creative storytelling to teach listeners about health and metabolism.

In this episode, we dive into: 

  • How metabolic health relates to Covid-19 (9:21) 
  • What is metabolic health (13:24) 
  • How Covid-19 can hijack metabolic health (15:41) 
  • How poor metabolic health and insulin resistance can make someone more likely to get Covid-19 (19:57) 
  • Vaccination and severe Covid-19 risk (22:21) 
  • Children, metabolic health, and Covid-19 (31:12) 
  • The ABCDS to better metabolic health (42:28) 
  • Lab tests for metabolic health (1:02:05) 

Also mentioned in this episode:

For more on Dr. Ronesh, you can follow him on Instagram @roneshsinhamd, on Facebook @southasiansolution, on Twitter @roneshsinha, on YouTube @roneshsinha, and through his website Check out his podcast, The Meta Health Podcast at Get his book, The South Asian Health Solution: A Culturally Tailored Guide to Lose Fat, Increase Energy, and Avoid Disease here.

For more on Dhru Purohit, be sure to follow him on Instagram @dhrupurohit, on Facebook @dhruxpurohit, on Twitter @dhrupurohit, and on YouTube @dhrupurohit. You can also text Dhru at (302) 200-5643 or click here.

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Wishing you health and happiness,
Mark Hyman, MD
Mark Hyman, MD


Mark Hyman, MD

Mark Hyman, MD is the Founder and Director of The UltraWellness Center, the Head of Strategy and Innovation of Cleveland Clinic's Center for Functional Medicine, and a 13-time New York Times Bestselling author.

If you are looking for personalized medical support, we highly recommend contacting Dr. Hyman’s UltraWellness Center in Lenox, Massachusetts today.


If you are looking for personalized medical support, we highly recommend contacting Dr. Hyman’s UltraWellness Center in Lenox, Massachusetts today.

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