Unlocking the Power of Your Mitochondria to Age in Reverse with Dr. Steven Gundry



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Chances are, you’ve heard a lot of buzz about the ketogenic (or keto) diet. This high-fat, low-carb approach to eating has become extremely popular in recent years for helping with everything from weight loss to cognition.

One cornerstone of the ketogenic diet is the idea that ketones are a powerful alternative fuel source for the human body. But as it turns out, ketones are not the magical fuel source they’ve been made out to be; in fact, the body cannot run on ketones and fats alone. Over the long term, a very low-carb diet can lead to muscle wasting and poor cognitive health.

Today on The Dhru Purohit Podcast, Dhru talks with Dr. Steven Gundry about the new science about what actually makes a keto diet so successful: a cellular process known as “mitochondrial uncoupling.” Dr. Gundry shares why it’s the key to reversing your age and living your best, healthiest life. 

Dr. Gundry is a renowned heart surgeon, New York Times bestselling author, and medical researcher. He is the author of Diet Evolution, The Plant Paradox, The Plant Paradox Cookbook, The Plant Paradox 30, The Longevity Paradox, and his latest book, Unlocking the Keto Code. After a distinguished career as a professor and chairman of cardiothoracic surgery at Loma Linda University, Dr. Gundry changed his focus to exterminating modern diseases with dietary changes. He is the Director and Founder of the International Heart & Lung Institute, as well as the Center for Restorative Medicine in Palm Springs and Santa Barbara, CA. He is also the cofounder of his own supplement and health-food line, GundryMD, and the host of the weekly Dr. Gundry Podcast.

In this episode, we dive into: 

  • Lifestyle factors that are contributing to metabolic inflexibility (3:48)
  • Understanding the history of ketones and what we got wrong about using them as fuel (7:33)
  • Mitochondrial uncoupling and how it impacts cellular aging (20:02)
  • Brown fat and mitochondrial uncoupling (27:12)
  • Why getting into ketosis is so difficult (29:04)
  • Traps of a keto diet (44:51)
  • The keys to mitochondrial uncoupling (1:05:44)
  • Dairy and the connection to longevity (1:29:06)
  • Traditional keto diet vs. Unlocking The Keto Code program (1:41:03)
  • Two powerful mitochondrial uncouplers (1:44:26)

Also mentioned in this episode:

For more on Dr. Gundry, follow him on Instagram @drstevengundry, Facebook @drstevengundry, Twitter @drgundry, YouTube @drstevengundry, and through his website, drgundry.com. Get his book, Unlocking The Keto Code, here, and listen to his podcast here.

For more on Dhru Purohit, follow him on Instagram @dhrupurohit, Facebook @dhruxpurohit, Twitter @dhrupurohit, and YouTube @dhrupurohit. Text Dhru at 302-200-5643 or click here

Interested in joining Dhru’s Facebook community? Submit your request to join here.

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Wishing you health and happiness,
Mark Hyman, MD
Mark Hyman, MD


Mark Hyman, MD

Mark Hyman, MD is the Founder and Director of The UltraWellness Center, the Head of Strategy and Innovation of Cleveland Clinic's Center for Functional Medicine, and a 13-time New York Times Bestselling author.

If you are looking for personalized medical support, we highly recommend contacting Dr. Hyman’s UltraWellness Center in Lenox, Massachusetts today.


If you are looking for personalized medical support, we highly recommend contacting Dr. Hyman’s UltraWellness Center in Lenox, Massachusetts today.

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