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Episode 906

The Doctor's Farmacy

The Science of Weight Loss: What You Need to Know

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Why is it so hard to lose weight and keep it off? On this episode of “The Doctor’s Farmacy,” we explore the intricate science of weight gain and metabolism, debunking common myths about calorie counting and your diet. Emphasizing the importance of food quality over quantity, I’ll examine how modern diets high in refined carbs and sugars contribute to obesity. By investigating root causes and offering a holistic approach, I’ll provide you with a science-backed roadmap to achieving sustainable weight loss and optimal metabolic health.

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Show Notes

Obesity Energetics: Body Weight Regulation and the Effects of Diet Composition (Gastroenterology)
Comparison of dietary macronutrient patterns of 14 popular named dietary programmes for weight and cardiovascular risk factor reduction in adults: systematic review and network meta-analysis of randomised trials (BMJ)
The effect of three different ad libitum diets for weight loss maintenance: a randomized 18-month trial (European Journal of Nutrition)
Trends in energy intake among adults in the United States: findings from NHANES (American Journal of Clinical Nutrition)
Consumption of added sugars is decreasing in the United States (American Journal of Clinical Nutrition)
Discrepancy between the Atwater factor predicted and empirically measured energy values of almonds in human diets (American Journal of Clinical Nutrition)
Walnuts Consumed by Healthy Adults Provide Less Available Energy than Predicted by the Atwater Factors (Journal of Nutrition)
Measured energy value of pistachios in the human diet (British Journal of Nutrition)
Metabolizable Energy from Cashew Nuts is Less than that Predicted by Atwater Factors (Nutrients)
Counting Calories: How under-reporting can explain the apparent fall in calorie intake (Behavioural Insights)
Calorie Estimation in Adults Differing in Body Weight Class and Weight Loss Status (Canadian Institute of Health Research)
The effect of dietary carbohydrate and calorie restriction on weight and metabolic health in overweight/obese individuals: a multi-center randomized controlled trial (BMC Medicine)
Weight Loss with a Low-Carbohydrate, Mediterranean, or Low-Fat Diet (NEJM)
Trends in Consumption of Ultraprocessed Foods Among US Youths Aged 2-19 Years, 1999-2018 (JAMA)
Effects of dietary glycemic index on brain regions related to reward and craving in men (The American Journal of Clinical Nutrition)
Systems biology, toxins, obesity, and functional medicine (Alternative Therapies in Health and Medicine)
Stress may add bite to appetite in women: a laboratory study of stress-induced cortisol and eating behavior (Psychoneuroendocrinology)