The Science of Erectile Dysfunction and Unexpected Ways to Treat It

Episode 863 1h 2m


A decrease in libido or difficulty in achieving or maintaining an erection during sex are tell-tale signs of erectile dysfunction, and they can be uncomfortable to address. Sure, aging and performance anxiety are part of the story, but believe it or not, erectile dysfunction is not just about sexual health. It’s often the first clue of bigger health issues.

In this episode of my Health Bites series, I explore the root causes of erectile dysfunction, delving into the limitations of conventional medicine, the little blue pill, and how we can utilize the power of Functional Medicine by making changes to our diet, lifestyle, and even trying things like supplements, peptides, and hormone therapy.

Recommended Lab Testing:

  • Sex Hormone Binding Globulin (SHBG)
  • Testosterone:
    • Free T: Optimal: > 30 pg/dL
    • Total T: Free T + Bound T
      • Optimal: > 500 ng/dL - but reference ranges are < 200 or < 300
      • Total can be normal, but can still suffer from symptoms of low T if SHBG is high
  • Estradiol:
    • Optimal range: (30-50 ng/dL)
  • LH
  • FSH
  • Prolactin
  • HsCRP
  • Toxins: heavy metals
  • Leptin
  • Adiponectin
  • HbA1c
  • Fasting insulin
    • Optimal: 2-5 uIU/mL
  • Stress hormones - cortisol, DHEA
  • Cardiovascular labs
    • Lipoprotein fractionation
  • Thyroid hormones


This episode is brought to you by MitoPure, and Rupa Health. The Doctor’s Farmacy podcast works with a select group of sponsors to allow for ongoing production and allow it to be zero-cost to anyone who wishes to listen to and watch the podcast.

Topics Covered

  • The prevalence of erectile dysfunction


  • The root cause of low testosterone


  • The conventional medicine approach to treating erectile dysfunction


  • How do Viagra and ED drugs work?


  • The Functional Medicine approach to treating erectile dysfunction: diagnostic testing


  • Root causes of sexual dysfunction


  • Diet, lifestyle, and supplements to improve sexual dysfunction


1 of 7

Host & Guests


Automatically generated. Please forgive any typos or errors in the following transcript. It was generated by a third party and has not been subsequently reviewed by our team.

Dr. Mark Hyman:
Coming up on this episode of the Doctor's Farmacy, it's all connected, right? It's not just ed, it's heart disease, diabetes, pre-diabetes, insulin resistance. It's all one problem. And one of the major ways that manifests is by damaging the lining of your blood vessels leading to less nitric oxide and hardening the arteries impaired blood flow. This is really a sign that you might have some cardiovascular disease, so you really want to pay attention if you're having erectile dysfunction because it's not just about sex, it's about your overall health.
Have you experienced a loss of libido recently? Are you carrying a little excess belly fat? Are you losing or having a hard time putting on lean muscle? What about an uptick in impotence?..

Want to read the full transcript for free?

Enter your name and email to sign up for our newsletter and unlock the transcript

Back to Content Library
Ep. 863 - The Science of Erectile Dysfunction and Unexpected Ways to Treat It