Getting to the Root Cause of Autoimmune Disease: A Functional Medicine Approach

Episode 878 1h 20m


Functional Medicine offers patients many things, especially hope and understanding. Autoimmune disease is a prime example: Rather than condemning patients to a lifetime of symptom management through medication, functional practitioners dig to find the “why,” to address the underlying causes with individualized, multimodal support to create lasting improvement and systemic healing. My guest today, Dr. Sara Gottfried, is a physician, researcher, author, and educator passionate about changing the way we view and treat autoimmunity. When we dig deeper, we always find out there is more going on below the surface. I know you’ll love this conversation as much as I did.


This episode is brought to you by Rupa Health, Cozy Earth, and Magnesium Breakthrough. The Doctor’s Farmacy podcast works with a select group of sponsors to allow for ongoing production and allow it to be zero-cost to anyone who wishes to listen to and watch the podcast.

Topics Covered

  • What is a “trauma signature” and what is its role in autoimmunity?


  • Why we’ve seen an explosion of autoimmune diseases with a lack of explanation


  • Hidden autoimmunity triggers you might be surprised to learn about


  • The test panel Sara runs on her patients


  • How our history and ancestors inform our current state of health


  • Sara’s stack for reducing cortisol and why trauma has to be considered


  • How Trauma biologically impacts you through the PINE system


  • Psychedelic therapy and other healing states of consciousness, plus Sara’s personal experience using them


  • Sara’s multimodal approach to resetting biology and psychology


  • Leaky gut and healing the microbiome


  • What Sara wishes she told her 20-year-old self about life


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Resources Mentioned

Host & Guests


Automatically generated. Please forgive any typos or errors in the following transcript. It was generated by a third party and has not been subsequently reviewed by our team.

Dr. Mark Hyman:
Coming up on this episode of the Doctor's Pharmacy

Dr. Sara Gottfried:
In a group of people from San Diego who were members of Kaiser Permanente, they found that when they take these people age 40 to 65, and they ask them about adverse childhood experiences using this questionnaire, a score of zero was no drama, but a score of one or higher was associated with a greater risk of chronic disease.

Dr. Mark Hyman:
Welcome to Doctor's Pharmacy. I'm Dr. Mark Hyman. That's pharmacy with enough place for conversations that matter. In today's conversation with Dr. Sarah Godfried, I think you're going to find fascinating because it dives deep into the topic of inflammation, autoimmunity, and hormonal balance. So we..

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Ep. 878 - Getting to the Root Cause of Autoimmune Disease: A Functional Medicine Approach