A Root Cause Approach to Hyperthyroidism and Graves’ Disease

Episode 65 35m


The thyroid gland is a small gland located in your neck that is part of your endocrine or hormonal system. It produces two major thyroid hormones, and the overproduction of these hormones is termed hyperthyroidism. Sixty to seventy percent of individuals with hyperthyroidism suffer from an autoimmune condition called Graves’ disease. So, what is driving these issues and how can that information be used to treat the root causes of hyperthyroidism and Graves’ disease? In this episode, Dr. Hyman sits down with Dr. George Papanicolaou to discuss how they work with patients to treat the root causes of hyperthyroidism and Graves’ disease. They discuss topics including environmental toxin exposure, the role of gut health in driving autoimmune disease, using thyroid hormone replacement therapy, and much more. George Papanicolaou is a graduate of the Philadelphia College of Osteopathic Medicine and is Board Certified in Family Medicine from Abington Memorial Hospital. He is also an Institute for Functional Medicine Practitioner. Upon graduation from his residency he joined the Indian Health Service. He worked on the Navajo reservation for 4 years at the Chinle Comprehensive Medical Facility where he served as the Outpatient Department Coordinator. In 2000, he founded Cornerstone Family Practice in Rowley, MA. He practiced with a philosophy centered on personal relationships and treating the whole person, not just not the disease. He called that philosophy “Whole Life Wellness”. Over time as the healthcare system made it harder for patients to receive this kind of personal care Dr. Papanicolaou decided a change was needed. He began training in Functional Medicine through the Institute of Functional Medicine. In 2015, he established Cornerstone Personal Health – a practice dedicated entirely to Functional Medicine. Dr. Papanicolaou joined The UltraWellness Center in 2017. This episode is sponsored by Rupa Health and Paleovalley. Rupa Health is a place for Functional Medicine practitioners to access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, Great Plains, and more. You can check out a free live demo with a Q&A or create an account at RupaHealth.com. Paleovalley is offering 15% off your entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. In this conversation, Dr. Hyman and Dr. Papanicolaou discuss:
  • Characteristics and symptoms of hyperthyroidism and Graves’ disease
  • Common autoimmune issues that cluster with hyperthyroidism and Graves’ disease
  • Thyroid supporting nutrients
  • The link between autoimmune disease, gut health, gluten sensitivity, and Celiac’s disease
  • Traditional vs Functional Medicine approaches to testing, diagnosing, and treating hyperthyroidism and Graves’ disease
  • Hormone replacement therapy
  • Patient cases they have treated with hyperthyroidism and Graves’ disease

Resources Mentioned

Host & Guests


Automatically generated. Please forgive any typos or errors in the following transcript. It was generated by a third party and has not been subsequently reviewed by our team.

Announcer: : Coming up on this episode of The Doctor's Farmacy. Dr. George Papanicolaou: I don't think that there's one person with an autoimmune disease I've treated that hasn't had some gut issue that had to be dealt with that was part of reducing their autoimmune process and getting them into remission. Dr. Mark Hyman: Welcome to The Doctor's Farmacy. I'm Dr. Mark Hyman, and that's farmacy with an F, a place for conversations that matter. Today, we're talking about ... On our special episode of House Call with Dr. George Papanicolaou, one of our extraordinary docs at the UltraWellness Center here in Lenox, Massachusetts, we're going to talk about thyroid. Most people struggle in this country with low thyroid. It affects one in five women, one in 10 men...

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Ep. 65 - A Root Cause Approach to Hyperthyroidism and Graves’ Disease