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The UltraMind Solution: Key #2 Balance Your Hormones

The UltraMind Solution: Key #2 Balance Your Hormones

WELCOME BACK TO my series of blogs on my new book, The UltraMind Solution.

Now for today’s blog …

Most of us are living life completely out of balance. But so many symptoms we come to accept as “normal” are just signs of imbalance–and the type of imbalance that affects almost everyone in our society is hormonal imbalance.

Let me ask you:

  • Do your mood and energy swing up and down, making your life crazy?
  • Do you crave sugar or salt?
  • Are you overweight and putting on more and more belly fat?
  • If you are a woman, do you have premenstrual syndrome or painful or heavy periods?
  • Are you depressed?
  • Do you sleep poorly?
  • Are you less interested in sex?
  • Do you have thinning hair, dry skin, and feel sluggish in the mornings?
  • Do you feel tired but wired?
  • Do you have to drink coffee every morning just to wake up and a few glasses of wine every night just to calm down?

If so, you are not alone. In fact, this is how most Americans feel, because we are living out of harmony with our natural biological rhythms–and our hormones are all over the place.  The hormones that cause the most mental misery are your stress hormones, your thyroid hormone, your sex hormones, and your major blood-sugar control hormone, insulin.

In this blog, I want to teach you about three very common major hormonal imbalances and how you can rebalance these areas of your biochemistry so you can achieve an UltraMind: insulin, thyroid, and sex hormone imbalances. We will discuss stress hormones in Part 8 of this series.

Hormonal Imbalance #1: Insulin Imbalance

If you crave sugar or bread, feel weak and irritable at 3 or 4 o’clock in the afternoon, skip breakfast or eat a big muffin or bagel for breakfast, or have extra belly fat, you likely have serious blood sugar and insulin problems, which can cause depression, dementia, and panic disorder.

Just look down at your belly–if it’s sticking out or jiggles when you jump up and down, you have a problem.

We have seen an extraordinary increase in sugar consumption, from 10 pounds per person per year at the beginning of the 19th century to 158 pounds per person per year at the beginning of the 21st century.

In fact, more money is spent at gas stations on junk food than on gas!  We spend more money on processed and junk food than on new cars, new computers and higher education–combined!

That’s why 100 million Americans suffer from insulin resistance, or “pre-diabetes.” This condition is a problem by itself and causes “pre-dementia,” also known as mild cognitive impairment.  In fact, some scientists are now calling Alzheimer’s disease “type-3 diabetes”!

We are now seeing type-2 diabetes in children. Could this mean they will get Alzheimer’s as early as their 30’s and 40’s?

And what about sugar and depression? Researchers found that people with symptoms of depression were 42 percent more likely to develop diabetes than those without depressive symptoms. They also found that the more serious the symptoms, the higher the risk of diabetes.

“More than half of aging men will lose their sexual function, their testosterone levels will drop, and their estrogen levels will rise, making men more like women.”

So what’s the cure?

  • Balance your blood sugar by cutting out flour and sugar (especially high-fructose corn syrup).
  • Eat whole foods and make sure you have some protein like eggs, nuts, or a protein shake for breakfast.
  • Don’t forget to get moving. Exercise is the magic potion for your brain and your belly fat.

Hormonal Imbalance #2: Thyroid Imbalance

Insulin isn’t the only hormone that can get out of balance. There’s another hormone imbalance that affects one in five women and one in 10 men – most of whom don’t even know they have it.

I’m talking about an imbalance of thyroid hormones.

  • Are you cold all the time?
  • Do you have dry skin, thinning hair, weak fingernails, a puffy face, swelling of your hands and feet, constipation, or trouble getting out of bed in the morning?
  • Do you seem to forget things easily?

If so, you might have a low-functioning thyroid.

A 73-year-old woman once came to see me because she had fatigue, sluggishness, poor memory, slight depression, dry skin, constipation, and a little fluid retention. When she visited her previous doctor, he said, “Well, what do you expect? You’re 73 – and this is what 73 is supposed to feel like.”

I don’t believe that is true. I believe that most of the symptoms of aging we see are really symptoms of abnormal aging or dysfunction that are related to imbalances in our core body systems.

This patient had a sluggish thyroid.

By simply replacing her missing thyroid hormone, supporting her nutrition, and implementing some simple lifestyle changes, she went from feeling old to feeling alert, energetic, and youthful. Plus, all of her other symptoms cleared up.

And research supports this. Studies have shown that older people with “sub-clinical” hypothyroidism have four times the risk of developing depression.(1) Yet many doctors prescribe antidepressants before they take a good hard look at the thyroid.

Your thyroid hormone is critical for making new brain cells (neurogenesis), particularly in the hippocampus, the part of the brain that is responsible for mood and memory.(2)

You might need the help of your doctor and prescription thyroid medication if your thyroid is not optimally balanced.

Here are some tips to help you along the way:

  • Get properly tested, as I explain in my book, The UltraMind Solution.
  • Get enough thyroid-supportive nutrients, including iodine, selenium, zinc, vitamin D, and omega-3 fats.
  • Take thyroid hormone replacement if your tests show you are not optimally balanced. Remember, most of the common medications out there don’t take care of this problem. People often need a little bit of T3–the active thyroid hormone–added to their treatment (even if they are already on other thyroid hormones.

Hormonal Imbalance #3: Sex Hormone Imbalances

Here’s some headline news.

Did you know:

  • “Seventy-five percent of women were found to have a mutant gene that threatens their relationships, work, and well-being.”
  • “More than half of aging men will lose their sexual function, their testosterone levels will drop, and their estrogen levels will rise, making men more like women.”

These are the beliefs that we all unconsciously accept.

Women are defective, flawed, and broken–and destined to suffer throughout their reproductive lives from mood and behavior swings that are the result of the three P’s: Puberty, premenstrual syndrome (PMS), and perimenopause. This is the “genetic flaw” that supposedly threatens them.

As they age, men–if you believe all the television commercials–supposedly need the “little blue pill” just to be men again.

  • Is this a “normal” part of being a woman or a man?
  • Is it the product of some defective, mutant gene?
  • Why do sex hormone levels drop up to 90 percent during the aging process?
  • Are we destined to suffer from impaired mood, muscle loss, poor sleep, memory difficulties, and sexual problems?

Of course not!

This suffering related to your reproductive life cycle is unnecessary. It is not bad luck, but bad habits, such as drinking and smoking, eating a high-sugar and refined-carbohydrate diet, being exposed to environmental toxins, and being chronically stressed.

To think that 75 percent of women have a design flaw that gives them PMS and requires medical treatment is just absurd. To think that we all have to dwindle, shrivel, and lose our emotional, physical, and sexual vitality is a burdensome, self-fulfilling prophecy.

We now have endless examples of balance and thriving at any age. One of my 81-year-old female patients recently told me, with a twinkle in her eye, about her new boyfriend and their wonderful love life.

PMS, menopausal symptoms, and andropause are all signs of imbalances in your sex hormones. They are not the result of mutant genes that destroy our sexual vitality as we age.

Instead, they are treatable symptoms of underlying imbalance in one of the core systems in your body. Get your sex hormones back in balance, and these problems usually disappear.

Male Hormonal Problems

If you are a man older than age 50, you might be getting flabby and feeling less interested in sex.

Do you see the hair on your legs and chest disappearing?

Are you getting “man boobs”?

If so, you might be low in testosterone, which makes you depressed, unmotivated, and mentally dull.

The solutions are simple:

  • Lose belly fat
  • Build muscle
  • Consider using topical testosterone cream or gel

Female Hormonal Problems

If you have headaches, breast tenderness, fluid retention, mood swings, and irritability in the days or weeks before your menstrual period, you might have too much estrogen and not enough progesterone. This can make you feel crazy.

Let me tell you the story of a patient of mine with premenstrual dysphoric disorder, or PMDD. She was barely able to function. She suffered three weeks out of every month with severe physical symptoms and debilitating depression. Was she deficient in Prozac (or Prozac renamed Sarafem to treat PMS)?

I don’t think so.

She was 37 years old. She had severe depression, fatigue, anxiety, and food and sugar cravings that led to overeating and 20 pounds of weight gain.  She also had joint pains, breast tenderness, heavy bleeding, hot flashes, dry skin, acne, hair loss, trouble with memory, poor sleep, and no sex drive.

She didn’t drink alcohol, but was a big coffee drinker. She started the day with a bagel and cheese, had a cafeteria lunch, chocolates in the afternoon, and a healthy dinner, followed by ice cream, chips, and Cheerios.  She also complained of gas and bloating.  And she ate a lot of dairy products.

We know that sugar, caffeine, alcohol, stress, and lack of exercise all contribute to worsened PMS(3) and all hormonal imbalances including menopause and andropause.(4)

It is also true that dairy consumption can worsen hormonal imbalances because of all the hormones in milk.(5)(6) Even organic milk can come from pregnant cows, jacking up hormones levels.(7)

So I helped her change her diet, cut out the sugar and caffeine, eliminate food allergens, take a few supplements and herbs, and do a little exercise. Within just one menstrual cycle her life changed.

All her symptoms resolved, she lost weight, and she increased her energy dramatically. Her mood stabilized (meaning her depression evaporated), and her acne and dry skin went away–all without medication.

Here’s what to do:

  • Eat a diet of whole foods that are low in sugar and refined carbs, caffeine, and alcohol.
  • Load up on broccoli, collard greens, and kale, which help balance hormones.
  • Supplement with vitamin B6, magnesium, evening primrose oil, and fish oil.
  • Get regular exercise.

Balancing your hormones is a process–and sometimes it has little twists and turns. But by sticking with it, you can become vital, happy, alert, brilliant, and thriving.

And if you need more help it’s in my book: The UltraMind Solution.

Remember, you can get a free sneak preview by going here:

But beware: there may be some serious side effects from balancing your hormones …  Some people notice a significant spike in their sex drive and pleasure!

In my next blog you will learn how brain inflammation has been linked to everything from autism to Alzheimer’s, from depression to ADHD. Our brains are on fire. Find out why and what to do about it.

Now I’d like to hear from you …

Do you suffer from any of the symptoms listed above?

Have you been told you have an imbalance of hormones?

What have you tried to balance your hormones?

Please leave your thoughts by adding a comment below–but remember, we can’t offer personal medical advice online, so be sure to limit your comments to those about taking back our health!

To your good health,

Mark Hyman, MD

PS–Remember, you can download a free sneak preview of The UltraMind Solution right now by going to .

And since I know many of you have friends, family members, or coworkers who may also suffer from a broken brain, please pass this message along to them. It may provide them the hope that they’ve been looking for.

PPS–You can also get your own copy of The UltraMind Solution DVD by Dr. Mark Hyman, M.D.


(1) Chueire VB, Romaldini JH, Ward LS. Subclinical hypothyroidism increases the risk for depression in the elderly. Arch Gerontol Geriatr. 2007 Jan-Feb;44(1):21-8. Epub 2006 May 5.

(2) Montero-Pedrazuela A, Venero C, Lavado-Autric R, Fernández-Lamo I, García-Verdugo JM, Bernal J, Guadaño-Ferraz A. Modulation of adult hippocampal neurogenesis by thyroid hormones: implications in depressive-like behavior. Mol Psychiatry. 2006 Apr;11(4):361-71.

(3) Rasheed P, Al-Sowielem LS. Prevalence and predictors of premenstrual syndrome among college-aged women in Saudi Arabia. Ann Saudi Med. 2003 Nov-Dec;23(6):381-7.

(4) Tan RS, Pu SJ. The andropause and memory loss: is there a link between androgen decline and dementia in the aging male? Asian J Androl. 2001 Sep;3(3):169-74. Review.

(5) Rich Edwards JW, Ganmaa D, Pollak MN, Nakamoto EK, Kleinman K, Tserendolgor U, Willett WC, Frazier AL.Milk consumption and the prepubertal somatotropic axis.Nutr J. 2007 Sep 27;6:28.

(6) [No authors listed]Milk, hormones and human health, 10/23-25/2006, Boston. J Mammary Gland Biol Neoplasia. 2007 Dec;12(4):315

(7) Pape-Zambito DA, Magliaro AL, Kensinger RS. Concentrations of 17beta-estradiol in Holstein whole milk. J Dairy Sci. 2007 Jul;90(7):3308-13.

Mark Hyman MD is the Medical Director at Cleveland Clinic’s Center for Functional Medicine, the Founder of The UltraWellness Center, and a ten-time #1 New York Times Bestselling author.

Comments (26)

  • Hi Mark, thanks for the great post. I have low thyroid caused by hashimotos (autoimmune). I have had improved results from taking selenium, vitamin D, zinc, reducing sugar intake and sorting out some adrenal problems. I have had to reduce my thyroid medication as these supplements have improved my blood results. I notice that there are a lot of reports of people resolving other autoimmune conditions on your website and others through a range of treatments including diet, removing toxins, allergens etc. do you have any case studies of this sort of success with hashimotos? I notice you say you may need T3, but is it not possible to rectify the immune response and restore thyroid function and therefore no longer need the thyroid meds like you seem to have done with other autoimmune conditions?
    Thanks again – you and your website are inspirational.

    • Thank you for your message and your interest in Dr. Hyman’s work. Your question and constellation of symptoms represents a complex medical condition. Questions regarding conditions like these cannot be answered in a responsible manner via the Internet.

      Wishing You the Best of Health!
      Dr. Hyman Staff

  • I have cysts on my thyroid, I go in for ultrasound in a few days. I have all the symptoms of hypothyroidism except one, low heart rate. I have had the symptoms for many years and now have parathesis neuropathy. I cannot convince my Dr I have a thyroid problem because her blood test on thyroid always comes out in the “normal” range. What can I do to convince her I’m not “chasing for a cause” of the neuropathy?

    • Hi Sherry,

      In order to provide you the proper care you need we hope you will seek the attention of a local qualified Functional Med practitioner soon. To locate a doctor near you who practices functional medicine like Dr. Hyman, go to and scroll down to where it says “locate a practitioner” and enter your location. Progress accordingly from there.

  • Woah this weblog is wonderful i really like reading your posts. Keep up the good work! You already know, lots of individuals are hunting around for this info, you can help them greatly.

  • I really like reading your information. I have hypothyroidism, fatty liver, cysts on my thyroid, my testosterone and DHEA are very high, and my progesterone is low. I’m a big mess. I don’t take any kind of prescription drugs. I do take supplements to help my thyroid, like selenium, iodine, and vit D. I don’t feel like it has helped much. I do go to a Dr. that goes by nutrition and supplements. I am currently reading your book The Ultra Mind Solution. Do you have any other suggestions that you are able to tell me? Do you have any other books I should read? I also read your book, Ultra Prevention, and loved it. I recommend your book all the time. Thank You.

    • Dear Hannah,
      It sounds like you and your mom have a great plan in place! Yes, read the book and sign up for virtual nutrition coaching if you and she are interested in working 1-1 with Dr. Hyman’s trained nutritionists. For more information, please see:

      Yes, we would suggest you try and get a 2nd opinion locally too. There are many undiagnosed cases of autoimmune thyroiditis as well as low functioning thyroid. The proper diagnosis can be made by a practitioner who can interpret labs in the functional range. To locate a doctor near you who practices functional medicine like Dr. Hyman, go to and scroll down to where it says “locate a practitioner” and enter your location. Progress accordingly from there.

      In good health,
      The Nutrition Team

  • Hi Mark,
    There is a rising body of info about using iodine not only for thyroid health, but also for general health and immunity. There is a lot of contraversy about the doses and supplements appropriate for the case. It is not clear for
    me if it is good to have iodine for treating Hashimoto disease
    It would be interesting to know your opinion about this topic.

  • I had issues for several years with being highly symptomatic for hypothyroidism and I would go to endocrinologists in search of help, only to be told its in my mind. I found a Functional Medicine Doctor who was willing to listen and performed more reliable in depth testing to determine that I do have a problem. He immediately began treating me and I was amazed at the difference. It has been incredibly difficult to treat but things are much better, thankfully. I found your website to be extremely informative and I thank you for taking your time to invest so much into for us to read. WE need more awareness and for people to take charge of their medical care.

  • My 23 yr. old daughter has been diagnosed with Polycystic Ovarian syndrome and is beginning to show early symptoms of this condition. Does Dr. Hyman care for persons with this condition? If not, would he be able to make a personal recommendation of specialists in this field.

    • Hi Faye,
      Thank you for your interest In Dr. Hyman’s work. Unfortunately he cannot provide you personalized medical advice in this forum. In order to provide you the proper care you need we hope you will seek the attention of a local qualified Functional Med practitioner soon. To locate a doctor near you who practices functional medicine like Dr. Hyman, go to and scroll down to where it says “locate a practitioner” and enter your location. Progress accordingly from there.

      You can also make an appointment to be a patient at Dr.Hyman’s UltraWellness Center in Lenox, MA. Please go to:
      Wishing you the best of health,
      Dr. Hyman Staff

  • I see in your blog above you suggest eating whole vegies such as broccoli, greens and kale. I have read via the internet that these vegies are bad for your thyroid. That they can cause goiters. I absolutely love these vegetables and are so good for all around good health. There is much controversy on what is good vs bad to eat…..some say it’s fine, the next website says its bad. What are the definite “NO” foods to avoid??

    • Hi Alison,

      Dr. Hyman encourages you to consume these vegetables and not be concerned about their goitrogenic effect because eaten in moderation, they are perfectly healthy. This is a case of moderation as well as the benefits and pro’s outweighing the risks or the cons. If you have thyroid disease you might enjoy lightly cooking these vegetables and not eating them raw (or limiting how many raw servings you have to a couple per week). Please see Dr. Hyman’s nutrition coaching portal for a personalized plan to help you get the appropriate 1:1 support for learning more about food as medicine.

  • I have bought the UltraMind Solution book. I do not want to follow the exact outlined 6 week plan. I want to make my own. However, the book does not state how I can do this.

    I thought that there would be basic requirements of each type of food so that I can ensure that I will get an “UltraMind”

    Am I missing something?

    Thank you,

  • Hi,
    I crave salt and sugar at the sme time.i take birth control. I a a small frame woman. I weigh 5’2″ and weigh 126 but I have belly fat. I’m trying to understand the science of these cravings.

  • Thank you for this information. I’ve suffered from endometriosis for over 15 years, had 3 surgeries and years of hormone treatments. A couple months ago I read the Daniel Plan and the Disease Delusion, and as suggested in the first book, put my trust in the Lord for the power to change my diet and lifestyle. I first did the ten day detox which helped me think about changing my entire diet, especially to eliminate gluten and dairy. The first month I had no cramps but sill some endo pain. The second month I added supplements such as you recommend here for hormone balance. I had zero pain or cramps! I’ve never gotten increasingly better! I couldn’t have made these changes without the information you and others have provided and without the strength only the Lord can give.

  • I am 46 years old. I have had problems with acne since I was a teenager. I also have 7 children. I started to notice that whenever I was pregnant my skin would clear up…. so I’ve always wondered about the connection between hormones and acne… Do you have an opinion about why I had clear skin during pregnancy?

  • Hi my name is Elizabeth. I was diagnosed with having overactive hyperthyroidism. I was told they have to remove my gland from the right side and that I have a nodule that I’ve had for a long time that has to be remove as well. So they want to remove the right side of my thyroid. I’m losing a lot of calcium. I also had a bone density test which showed very lil density. I already had a hysterectomy and gallbladder removed. I need a different type of help. Please help!!

    • Hi Elizabeth,
      Thank you for your interest In Dr. Hyman’s work. Unfortunately he cannot provide you personalized medical advice in this forum. In order to provide you the proper care you need we hope you will seek the attention of a local qualified Functional Med practitioner soon. To locate a doctor near you who practices functional medicine like Dr. Hyman, go to and scroll down to where it says “locate a practitioner” and enter your location. Progress accordingly from there.
      Wishing you the best of health,
      Dr. Hyman Staff

  • I am reading this article in hopes for some insight into how to fix birth control induced hormonal imbalance.

    I am trying to get off of my birth control pill that I have been on for seven years. It has proven extremely difficult and challenging. My doctor has listened to my symptoms and thinks that I should start taking bio-identical hormone progesterone. I already have a clean diet and take vitamins and have tried all-natural supplements.

    I am wondering if I should have some kind of test done to ensure that I in fact have a estrogen dominance issue before taking the hormone?

    I am so desperate for relief from the anxiety, insomnia, uncontrollable emotions etc. that I am willing to try anything.
    I realize that this will take a while to fix itself but I am looking forward to feeling like myself again and better than when I was on bc. I am starting to connect the dots as far as ‘normal’ symptoms go and am now realizing everything that I thought was normal is not and probably a symptom of the bc all these years.

    Encouragement and advice is greatly appreciated! Thank you.

  • Dr. Hyman, What about Soto-pelle for sixty year old woman who has had a complete hysterectomy? What are your thoughts?