Tired And Wired: How To Heal Adrenal Fatigue 

Episode 706 1h 6m


When we experience stress–or any threat to our well-being–our brain goes on high alert, activating an ancient system designed to protect us from a wide variety of threats and dangers. Unfortunately, modern life is keeping most of us in a state of chronic stress activation. This puts our bodies in an ongoing state of survival mode and sets the stage for burnout, fatigue, and adrenal dysfunction.

Today on The Doctor’s Farmacy, I talk with Izabella Wentz all about adrenal dysfunction, how it develops, its common signs and symptoms, and how to support your adrenal function to reverse burnout. Stress is one of the most common causes of adrenal fatigue, as it creates an intense demand for hormones like cortisol and adrenaline to be released. Izabella walks us through the four types of chronic stress that can sabotage our adrenals: inflammation, circadian rhythm imbalances, nutritional deficiencies, and psychological stress. Most integrative doctors say that if you have adrenal fatigue, you need to test your adrenals, quit caffeine, sleep more, and take certain hormones, like DHEA. Izabella shares her Adrenal Transformation Protocol and explains how her approach is different.

We also discuss the role that gut health plays when it comes to adrenal balance, Izabella’s unique supplement and sleep protocols, and so much more. I hope you’ll tune in.


This episode is brought to you by Rupa Health, Cozy Earth, Butcher Box, and InsideTracker. The Doctor’s Farmacy podcast works with a select group of sponsors to allow for ongoing production and allow it to be zero-cost to anyone who wishes to listen to and watch the podcast.

Topics Covered

  • The start of Izabella’s personal issues with fatigue


  • How our body responds to chronic stress


  • Stages of adrenal dysfunction


  • Detecting adrenal issues


  • Four types of stress


  • Gut health and adrenal function


  • Why thyroid and adrenal dysfunction is so prevalent, especially in women


  • Restoring adrenal function


  • Understanding and working with your past trauma and triggers


  • Fixing your sleep issues


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Resources Mentioned

Host & Guests


Automatically generated. Please forgive any typos or errors in the following transcript. It was generated by a third party and has not been subsequently reviewed by our team.

Introduction: Coming up on this episode of The Doctor's Farmacy.

Izabella Wentz: One of the key stressors is blood sugar imbalances. So just eating too many carbs and too much sugar, and then not enough protein and fat. This is a really, really big stressor for many people.

Dr. Mark Hyman: Welcome to the Doctor's Farmacy. I'm Dr. Mark Hyman. That's pharmacy where we have a place for conversations that matter. And if you've ever struggled with fatigue or feel burnt out, or feel overstressed, or tired and wired when you go to bed and you don't know why, well, you're going to find out why today. Because we're going to have an amazing conversation with Izabella Wentz, who's an acclaimed thyroid specialist, a..

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Ep. 706 - Tired And Wired: How To Heal Adrenal Fatigue