The Hidden Connection Between Gut Health & Mental Health That Therapy and Drugs Cannot Fix

Episode 879 36m


Our global mental health crisis is growing at an exponential rate, with over half a billion people suffering from depression and anxiety; it’s time we rethink our understanding of the underlying root causes of mental health challenges.

From treating thousands of patients, I’ve learned that depression is not in your head. It’s in your body. More specifically, your gut. When your gut is unhealthy and inflamed, your brain is unhealthy and inflamed. In Functional Medicine, we know that the gut and the brain are intimately connected and that the health of one directly influences the health of the other.

In today’s Health Bites episode, we’re diving into the gut-brain connection and sharing Functional Medicine tools to support your gut health and, as a result, your mood and mental health.


This episode is brought to you by AG1, and Rupa Health. The Doctor’s Farmacy podcast works with a select group of sponsors to allow for ongoing production and allow it to be zero-cost to anyone who wishes to listen to and watch the podcast.

Topics Covered

  • Our global mental health crisis


  • The gut-brain connection


  • The story of Marks's broken brain


  • Features of the gut-brain axis


  • Gut hormones that send signals to your brain


  • Role of the gut microbiota in mood and mental health


  • How stress negatively impacts our gut microbiome


  • The link between leaky gut and poor mental health


  • The Functional Medicine approach to fixing the gut


  • The 5R Program for fixing your gut health


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Host & Guests


Automatically generated. Please forgive any typos or errors in the following transcript. It was generated by a third party and has not been subsequently reviewed by our team.

Dr. Mark Hyman: Coming up on this episode of the Doctor's Farmacy over the last 30 years, I've learned that depression is mostly not in your head, it's in your body. When your gut is unhealthy, your brain is unhealthy. Now, conventional medicine views these two things as completely separate and unrelated. Functional medicine. We know the gut and the brain are in connected and that the health of one directly impacts the other. Welcome to Doctors' Farmacy. I'm Dr. Mark Hyman, that's Farmacy with Anfa Place for conversations that matter. And today we're doing another special episode of Health Bites and we're talking about something really, really important, which is the role that your gut microbiome plays in your mental health. I'm going to say that again. The role..

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Ep. 879 - The Hidden Connection Between Gut Health & Mental Health That Therapy and Drugs Cannot Fix