The Functional Medicine Approach To Ending Migraines

Episode 34 46m


Migraines are a big problem for many people. These severe, nearly disabling headaches can occur anywhere from once a year to three to four times a week. They can last from hours to days. They are often associated with an aura, light sensitivity, nausea, vomiting, and severe throbbing pain on one or both sides of the head. And migraines can be caused by many different factors. This is where Functional Medicine comes in.

Functional Medicine is medicine by cause; not by symptom. It helps us discover the underlying triggers of disease. And the root cause of your migraine may not be in your head at all. In fact, migraines can be caused by things ranging from food sensitivities and allergies to hormonal imbalances, vitamin deficiencies, and more.

In this episode, Dr. Hyman sits down with Dr. Todd LePine to discuss the Functional Medicine approach to ending migraines. They explore how to identify and eliminate what might be causing your migraines and share specific patient migraine cases they have treated. Dr. LePine graduated from Dartmouth Medical School and is Board Certified in Internal Medicine, specializing in Integrative Functional Medicine. He is an Institute for Functional Medicine Certified Practitioner.

Prior to joining The UltraWellness Center, he worked as a physician at Canyon Ranch in Lenox, MA, for 10 years. Dr. LePine’s focus at The UltraWellness Center is to help his patients achieve optimal health and vitality by restoring the natural balance to both the mind and the body. His areas of interest include optimal aging, bio-detoxification, functional gastrointestinal health, systemic inflammation, autoimmune disorders and the neurobiology of mood and cognitive disorders.

Dr. LePine teaches around the world, and has given lectures to doctors and patients at American College for Advancement in Medicine (ACAM), Age Management Medicine Group (AMMG), the University of Miami Integrative Medicine Conference, The Kripalu Center in Lenox, MA, and is on the faculty for American Academy of Anti-Aging Medicine (A4M). Dr. LePine is the head of the Scientific Advisory Board for Designs for Health and a consultant for Diagnostic Solutions Laboratory. He enjoys skiing, kayaking, hiking, camping and golfing in the beautiful Berkshires, and is a fitness enthusiast.

In this episode, Dr. Hyman and Dr. LePine discuss:

  • The conventional vs Functional Medicine’s approach to preventing and treating migraines
  • The most common types of migraines, including menstrual migraines
  • The role of mitochondria in migraines, and the connection between migraines and seizures
  • The connection between gut health and migraines
  • How stress and lack of sleep can trigger migraines
  • Eliminating gluten and foods to treat migraines
  • Common nutrient deficiencies that can lead to migraines, including magnesium deficiency
  • How histamine sensitivity can be related to migraines
  • How your genetics can be a factor in driving migraines


This episode is brought to you by Simple Mills, and Apeel. The Doctor’s Farmacy podcast works with a select group of sponsors to allow for ongoing production and allow it to be zero-cost to anyone who wishes to listen to and watch the podcast.

Resources Mentioned

Host & Guests


Automatically generated. Please forgive any typos or errors in the following transcript. It was generated by a third party and has not been subsequently reviewed by our team.

Dr. Todd Lepine: There are certain foods which can trigger a migraine. Is it the food that's doing it or is it something in the food or it's how the food is actually being metabolized? That's a really key important feature is the connection between the gut, our food and the brain. Dr. Mark Hyman: Welcome to The Doctor's Farmacy. I'm Dr. Mark Hyman. That's Farmacy with an F, F-A-R-M-A-C-Y. A place for conversations that matter. If you've ever had a headache, you better listen up, especially if you've had a migraine because today we're having a special episode of The Doctor's Farmacy called House Call with my colleague and friend, Dr. Todd Lepine here at the UltraWellness Center in Lenox, Massachusetts. We see so much migraines. Todd has been..

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Ep. 34 - The Functional Medicine Approach To Ending Migraines