How To Prepare Our Bodies and Minds for The NEXT Pandemic with Dr. Austin Perlmutter



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Chronic diseases are the top risk factors for death and disability today. They’re also among the top risk factors for having worse outcomes from COVID-19. This implies that much of our risk for worse outcomes from this virus is a reflection of the choices we’ve made in the years and months leading up to the pandemic. In many ways, the stage was set for this pandemic long ago, because it’s not just about the virus—it’s also about the host, and we were already compromised from an immune perspective before COVID-19 existed. This means that we have an opportunity to start making the necessary changes to our physiology, so that we’re better prepared for the next pandemic.

On today’s episode of The Dhru Purohit Podcast, Dhru sits down with Dr. Austin Perlmutter, a board-certified internal medicine physician and New York Times bestselling author. He received his medical degree from the University of Miami and completed his internal medicine residency at Oregon Health and Science University in Portland Oregon. His focus is on helping identify and resolve the biological basis for “stuckness” in the body and brain, especially around decision-making. 

He hosts the Get The STUCK OUT podcast and is a co-producer of the Alzheimer’s – The Science of Prevention Docu-series. His writing is featured online on MedPage Today, Doximity, KevinMD, Medium, Psychology Today, MindBodyGreen, and He is the author of a recent review paper on the interfaces between immune function, depression, and COVID-19.

In this episode, we dive into:

  • How our epidemic of chronic diseases have predisposed us to worse outcomes from COVID-19 (4:34)
  • The importance of moving away from reactivity to solve our problems (12:03)
  • The intersection of COVID-19 and depression (16:02) 
  • What’s underlying depression (20:27) 
  • Dr. Perlmutter’s personal experience with anxiety and depression (25:52)
  • The connection between immune health and mental health (36:18) 
  • How to support and enhance our immune system (45:50) 
  • The importance of cutting out unnecessary stress (50:16)
  • The power of psilocybin and other psychedelic medicines for getting your brain unstuck (1:06:49)

For more on Dr. Austin Perlmutter you can follow him on Instagram @austinperlmutter, on Facebook @austinperlmuttermd, on Twitter @austinperlmd, on YouTube @austinperlmuttermd, and through his website. Check out his podcast Get The STUCK Out here.

Also mentioned in this episode:

For more on Dhru Purohit, be sure to follow him on Instagram @dhrupurohit, on Facebook @dhruxpurohit, on Twitter @dhrupurohit, and on YouTube @dhrupurohit. You can also text Dhru at (302) 200-5643 or click here.

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Wishing you health and happiness,
Mark Hyman, MD
Mark Hyman, MD


Mark Hyman, MD

Mark Hyman, MD is the Founder and Director of The UltraWellness Center, the Head of Strategy and Innovation of Cleveland Clinic's Center for Functional Medicine, and a 13-time New York Times Bestselling author.

If you are looking for personalized medical support, we highly recommend contacting Dr. Hyman’s UltraWellness Center in Lenox, Massachusetts today.


If you are looking for personalized medical support, we highly recommend contacting Dr. Hyman’s UltraWellness Center in Lenox, Massachusetts today.

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